Multivesicular emulsion drug delivery systems
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United States of America Patent
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Mar 23, 2004
Grant Date -
Mar 13, 2003
app pub date -
Aug 31, 2001
filing date -
Aug 31, 2001
priority date (Note) -
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Abstract
A topical delivery composition which employs a multivesicular emulsion in combination with a pharmaceutically/pharmacologically active agent is disclosed. The multivesicular emulsion is formed from a quaternary amine salt emulsifier such as behentrimonium methosulfate. The emulsion is multi-lamellar which is a series of concentric spheres or vesiculars of oil and water phase that can be seen microscopically. As a result, the active is time released over a sustained period rather than spike released as is common with most topicals.
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